Abstract
Engineering protease specificity has been a long sought research goal. New findings on OmpT, an outer membrane protease from Escherichia coli, reveal the remarkable success of a simple strategy.
MeSH terms
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Catalytic Domain
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Models, Molecular
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Protein Engineering*
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Serine Endopeptidases / chemistry
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Serine Endopeptidases / metabolism*
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Substrate Specificity
Substances
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Serine Endopeptidases
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omptin outer membrane protease