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Clin Vaccine Immunol. 2008 Jun;15(6):1024-7. doi: 10.1128/CVI.00009-08. Epub 2008 Apr 16.

Immunoglobulin G avidities in infants in Mexico after primary immunization with three doses of polyribosylribitol phosphate-tetanus toxoid Haemophilus influenzae type b vaccine.

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  • 1Departamento de Salud Pública, Facultad de Medicina, Universidad Nacional Autónoma de México, México D.F., México.


Serum immunoglobulin G concentrations and avidities specific to Haemophilus influenzae type b (Hib) were measured in 208 children living in Guadalajara and Mexico City. Protective concentrations were found in 98.9% and 100.0% of participants, respectively. Geometric mean concentrations differed between both populations and/or among age groups. Mean avidities differed only among the 7- to 12-month-old children. Diphtheria-tetanus-whole-cell pertussis-hepatitis B-Hib primary vaccination seems to induce protection in Mexican children.

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