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J Neurooncol. 2008 Aug;89(1):59-62. doi: 10.1007/s11060-008-9583-8. Epub 2008 Apr 15.

Cerebellar anaplastic astrocytoma in a teenager with Ollier Disease.

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  • 1Medical Center of Central Georgia, 840 Pine Street, Macon, GA 31201, USA. mswalid@yahoo.com

Abstract

INTRODUCTION:

Ollier Disease is a sporadic skeletal disorder with a predisposition to oncogenesis. It is estimated at around 1/100,000. We are presenting a young patient with Ollier Disease and high-grade astrocytoma.

CASE REPORT:

A 14-year-old, Caucasian male with Ollier Disease presented with a history of headaches, vomiting, blurred vision, and unsteady gait. Brain MRI with contrast showed a 41 x 55 mm mass in the posterior fossa with spotty enhancement, which pathology proved to be anaplastic astrocytoma.

CONCLUSION:

Despite the universal acceptance that Ollier Disease carries a high risk of developing malignancy there is very little in the literature about systematic screening. We recommended a cost-effective screening regime for these patients.

PMID:
18414790
[PubMed - indexed for MEDLINE]
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