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    CNS Spectr. 2008 Apr;13(4):301-3.

    Development of tics in a thirteen-year-old male following atomoxetine use.

    Sears J, Patel NC.

    Pediatric Neurology, Department of Child Health, University of Missouri-Columbia, Columbia, MO 65212, USA.

    Tics and Tourette syndrome are common comorbidities of patients diagnosed with attention-deficit/hyperactivity disorder (ADHD). One of the mainstay pharmacologic therapies for ADHD has been stimulants. However, this class of drugs has been associated with tic exacerbations, thus limiting their utility in this patients subgroup. Atomoxetine has been explored as an alternative treatment as one of the few non-stimulants available to treat ADHD. Early data identifies atomoxetine's influence on Tourette symptomatology to be not merely equivocal but potentially suppressive in the manifestation of tics. There are, however, case studies describing patients experiencing recurrences of tics following treatment with atomoxetine. We present a unique case of a patient, without any prior history of a movement disorder, who developed tics following a single dose of atomoxetine that did not improve until interventional therapy was initiated.

    PMID: 18408649 [PubMed - indexed for MEDLINE]

    Supplemental Content

    Patient drug information

    • Clonidine (Catapres®, Clorpres® (as a combination product containing Clonidine and Chlorthalidone))

      Clonidine is used alone or in combination with other medications to treat high blood pressure. Clonidine is in a class of medications called centrally acting alpha-agonist hypotensive agents. It works by decreasing your ...

    • Clonazepam (Klonopin®)

      Clonazepam is used alone or in combination with other medications to control certain types of seizures. It is also used to relieve panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks)....

    • Atomoxetine (Strattera®)

      Atomoxetine is used as part of a total treatment program to increase the ability to pay attention and decrease impulsiveness and hyperactivity in children and adults with ADHD. Atomoxetine is in a class of medications ca...