Future Oncol. 2008 Apr;4(2):271-87.

Clinical proteomics and breast cancer: strategies for diagnostic and therapeutic biomarker discovery.

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Institut Paoli-Calmettes and UMR599, Centre de Recherche en Cancérologie de Marseille, Département d'Oncologie Moléculaire, 232, Bd Sainte-Marguerite 13009 Marseille, France. bertuccif@marseille.fnclcc.fr

Abstract

A major challenge of breast cancer research is the identification of accurate biomarkers that improve screening, early diagnosis, prediction of aggressiveness, and prediction of therapeutic response or toxicity, as well as the identification of new molecular therapeutic targets. The new proteomic techniques promise to be valuable for identifying such tissue and serum markers. The different techniques currently applied to clinical samples of breast cancer and the most important results obtained are summarized in this review.

PMID:: 18407739; [PubMed - indexed for MEDLINE]

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Tumor Markers, Biological

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Review [Proteomics and breast cancer: a search for novel diagnostic and theragnostic biomarkers]. [Bull Cancer. 2010]
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Cited by 3 PubMed Central articles

Review Challenges for biomarker discovery in body fluids using SELDI-TOF-MS. [J Biomed Biotechnol. 2010]
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