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1: Ann Hum Genet. 1991 Oct;55(Pt 4):273-8.Links

The gene for human neurone specific ubiquitin C-terminal hydrolase (UCHL1, PGP9.5) maps to chromosome 4p14.

Edwards YH, Fox MF, Povey S, Hinks LJ, Thompson RJ, Day IN.

M.R.C. Human Biochemical Genetics Unit, Galton Laboratory, London.

Ubiquitin carboxy terminal hydrolase 1, UCHL1, is a neurone-specific protein involved in the ubiquitin-mediated proteolytic pathway. The gene for human UCHL1 has been mapped to chromosome 4 using the polymerase chain reaction to amplify specifically the human UCHL1 sequences in rodent/human somatic cell hybrid DNA. A regional assignment of this locus to 4p14 has been made by in situ hybridization to metaphase chromosomes using both tritium and fluorescently labelled probes.

PMID: 1840236 [PubMed - indexed for MEDLINE]