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Acta Paediatr. 2008 Jun;97(6):701-5. doi: 10.1111/j.1651-2227.2008.00750.x. Epub 2008 Apr 7.

Adiponectin: an intriguing hormone for paediatricians.

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  • 1Department of Pediatrics, Regina Margherita Children's Hospital, University of Turin, Turin, Italy. francesco.savino@unito.it

Abstract

Adiponectin, a protein hormone produced by adipocytes, is also found in breast milk, which in turn is implicated in childhood obesity prevention. Although a biological role for adiponectin has not been firmly established, clinical and experimental research indicates that it regulates lipid and glucose metabolism, affects foetal development, and exerts anti-inflammatory and antiatherogenic effects.

CONCLUSION:

This review demonstrates an emerging interest of paediatric research on adiponectin. A better understanding of adiponectin's bioactivity might clarify whether breast milk indeed prevents childhood obesity.

PMID:
18397349
[PubMed - indexed for MEDLINE]
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