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    Results: 2

    1.

    MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells.

    Nishioka C, Ikezoe T, Yang J, Takeuchi S, Koeffler HP, Yokoyama A.

    Leuk Res. 2008 Sep;32(9):1382-92. Epub 2008 Apr 3.

    PMID:
    18394702
    [PubMed - indexed for MEDLINE]
    2.

    Cotreatment with 17-allylamino-demethoxygeldanamycin and FLT-3 kinase inhibitor PKC412 is highly effective against human acute myelogenous leukemia cells with mutant FLT-3.

    George P, Bali P, Cohen P, Tao J, Guo F, Sigua C, Vishvanath A, Fiskus W, Scuto A, Annavarapu S, Moscinski L, Bhalla K.

    Cancer Res. 2004 May 15;64(10):3645-52.

    PMID:
    15150124
    [PubMed - indexed for MEDLINE]
    Free Article

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