Neurotherapeutics. 2008 Apr;5(2):339-44.

Deep brain stimulation in Tourette's Syndrome.

Ackermans L, Temel Y, Visser-Vandewalle V.

Source

Department of Neurosurgery, University Hospital Maastricht, Maastricht, The Netherlands.

Abstract

Tourette's Syndrome (TS) is a neuropsychiatric disorder characterized by motor and vocal tics, often associated with behavioral disorders. Symptoms often disappear before or during adulthood. The pathophysiology of TS is still a matter of considerable debate. Current knowledge of cortico-basal ganglia-thalamocortical circuits provide explanations for the beneficial effects of deep brain stimulation (DBS) on tics. When conservative treatment fails in patients with severe TS, DBS may be a therapeutic option. In 1999, thalamic DBS was introduced for intractable TS. Since then, multiple targets have been used in a small number of patients, including the globus pallidus pars interna and the nucleus accumbens. Inclusion and exclusion criteria have been formulated to identify good candidates for DBS.

PMID:: 18394575; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Review

MeSH Terms

LinkOut - more resources

Full Text Sources

Medical

Supplemental Content

Related citations

Review DBS in tourette syndrome: rationale, current status and future prospects. [Acta Neurochir Suppl. 2007]
Review DBS in tourette syndrome: rationale, current status and future prospects.
Visser-Vandewalle V. Acta Neurochir Suppl. 2007; 97(Pt 2):215-22.
Deep brain stimulation in Tourette's syndrome: two targets? [Mov Disord. 2006]
Deep brain stimulation in Tourette's syndrome: two targets?
Ackermans L, Temel Y, Cath D, van der Linden C, Bruggeman R, Kleijer M, Nederveen P, Schruers K, Colle H, Tijssen MA, et al. Mov Disord. 2006 May; 21(5):709-13.
Deep brain stimulation in Tourette's syndrome. [Mov Disord. 2007]
Deep brain stimulation in Tourette's syndrome.
Bajwa RJ, de Lotbinière AJ, King RA, Jabbari B, Quatrano S, Kunze K, Scahill L, Leckman JF. Mov Disord. 2007 Jul 15; 22(9):1346-50.
Review Issues related to deep brain stimulation for treatment-refractory Tourette's syndrome. [Eur Neurol. 2009]
Review Issues related to deep brain stimulation for treatment-refractory Tourette's syndrome.
Porta M, Servello D, Sassi M, Brambilla A, Defendi S, Priori A, Robertson M. Eur Neurol. 2009; 62(5):264-73. Epub 2009 Aug 19.
Review From psychosurgery to neuromodulation: deep brain stimulation for intractable Tourette syndrome. [World J Biol Psychiatry. 2009]
Review From psychosurgery to neuromodulation: deep brain stimulation for intractable Tourette syndrome.
Neuner I, Podoll K, Janouschek H, Michel TM, Sheldrick AJ, Schneider F. World J Biol Psychiatry. 2009; 10(4 Pt 2):366-76.

See reviews... See all...

Cited by 5 PubMed Central articles

The need for a proper definition of a "treatment refractoriness" in tourette syndrome. [Front Integr Neurosci. 2011]
The need for a proper definition of a "treatment refractoriness" in tourette syndrome.
Porta M, Sassi M, Menghetti C, Servello D. Front Integr Neurosci. 2011; 5:22. Epub 2011 Jun 6.
Deep brain stimulation: technology at the cutting edge. [J Clin Neurol. 2010]
Deep brain stimulation: technology at the cutting edge.
Shah RS, Chang SY, Min HK, Cho ZH, Blaha CD, Lee KH. J Clin Neurol. 2010 Dec; 6(4):167-82. Epub 2010 Dec 31.
In vivo impedance spectroscopy of deep brain stimulation electrodes. [J Neural Eng. 2009]
In vivo impedance spectroscopy of deep brain stimulation electrodes.
Lempka SF, Miocinovic S, Johnson MD, Vitek JL, McIntyre CC. J Neural Eng. 2009 Aug; 6(4):046001. Epub 2009 Jun 3.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Deep brain stimulation in Tourette's Syndrome.
Deep brain stimulation in Tourette's Syndrome.
Neurotherapeutics. 2008 Apr ;5(2):339-44.

PubMed
Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytoc...
Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase.
Free Radic Biol Med. 2000 Aug ;29(3-4):211-21.

PubMed
Nomenclature and taxonomy of the genus Salmonella.
Nomenclature and taxonomy of the genus Salmonella.
Int J Syst Evol Microbiol. 2005 Jan ;55(Pt 1):521-4.

PubMed
Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis...
Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis: a report from the children's oncology group.
Cancer Epidemiol Biomarkers Prev. 2005 Mar ;14(3):651-5.

PubMed
Targeted mutations of transforming growth factor-beta genes reveal important rol...
Targeted mutations of transforming growth factor-beta genes reveal important roles in mouse development and adult homeostasis.
Eur J Biochem. 2000 Dec ;267(24):6982-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: