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J Med Chem. 2008 May 8;51(9):2634-7. Epub 2008 Apr 8.

Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.

Carr G, Chung MK, Mauk AG, Andersen RJ.

Departments of Chemistry and Earth & Ocean Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z1, Canada.

Abstract

Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.

PMID: 18393489 [PubMed - indexed for MEDLINE]

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