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Angiology. 2008 Dec-2009 Jan;59(6):717-20. doi: 10.1177/0003319707311536. Epub 2008 Apr 2.

Carotid and femoral atherosclerosis in chronic hepatitis C: a 5-year follow-up.

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  • 1Department of Medical and Surgical Science, Clinica Medica II, Universit√† di Padova, Padova, Italy.


The objective of this study was to assess the progression of atherosclerosis in carotid and femoral arteries after a 5-year period using ultrasound in subjects with chronic hepatitis C and in controls matched for classic atherosclerotic risk factors. A total of 40 patients and 40 controls were assessed by echocolor Doppler in 2001 and in 2006 to evaluate plaque and intima-media thickness. The patients showed no changes in plaque and intima-media thickness during the 5-year period in all districts examined, whereas a significant increase in intima-media thickness in the carotid sections was recorded in the controls. Chronic hepatitis C seems to cause delay in the atherosclerotic process.

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