Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Congenit Heart Dis. 2007 Mar-Apr;2(2):104-9. doi: 10.1111/j.1747-0803.2007.00081.x.

Update on randomized clinical trials impacting clinical care in pediatric cardiac intensive care.

Author information

  • 1Division of Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. tabbutt@email.chop.edu


Clinical trials addressing the management of infants and children with congenital heart disease are challenged by low numbers of patients with a similar diagnosis (inadequate power), variation in management strategies between institutions (difficulty developing multicentered protocols), a rapidly evolving field (equipoise), and insufficient funding. This article summarizes the challenges and the results of some single-center and multicenter trials evaluating perioperative care of infants and children undergoing surgery for congenital heart disease.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Blackwell Publishing
    Loading ...
    Write to the Help Desk