Send to:

Choose Destination
See comment in PubMed Commons below
J Am Chem Soc. 2008 Apr 23;130(16):5408-9. doi: 10.1021/ja800747m. Epub 2008 Apr 1.

Tandem Michael addition/ylide epoxidation for the synthesis of highly functionalized cyclohexadiene epoxide derivatives.

Author information

  • 1State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, 354 FengLin Lu, Shanghai 200032, China.


A highly efficient diastereoselective synthesis of cyclohexadiene epoxide derivatives with a multi-stereocenter has been developed via a tandem ylide Michael addition/epoxidation. By employing a chiral sulfonium ylide, up to 96% ee can be achieved in good yields.

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Write to the Help Desk