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Diabetes Care. 2008 Jul;31(7):1389-91. doi: 10.2337/dc08-0194. Epub 2008 Mar 28.

Sex disparities in the treatment and control of cardiovascular risk factors in type 2 diabetes.

Author information

  • 1Department of Internal Medicine II, University of Cologne, Cologne, Germany. ioanna.berthold@uni-koeln.de

Abstract

OBJECTIVE:

To assess whether sex differences exist in the effective control and medication treatment intensity of cardiovascular disease (CVD) risk factors.

RESEARCH DESIGN AND METHODS:

We performed a cross-sectional analysis including 44,893 patients with type 2 diabetes (51% women). End points included uncontrolled CVD risk factors (LDL cholesterol > or =130 mg/dl, systolic blood pressure [SBP] > or =140 mmHg, and A1C > or =8%) and the intensity of medical management in patients with uncontrolled CVD risk factors. Multiple-adjusted odds ratios were calculated after stratification for the presence of CVD (present in 39% of the patients).

RESULTS:

Women with CVD were less likely to have SBP, LDL cholesterol, and A1C controlled and less likely to receive intensive lipid-lowering treatment. Women without CVD were less likely than men to have LDL cholesterol controlled with no differences in SBP or A1C control.

CONCLUSIONS:

Women with diabetes and CVD have poorer control of important modifiable risk factors than men and receive less intensified lipid-lowering treatment.

PMID:
18375411
[PubMed - indexed for MEDLINE]
PMCID:
PMC2453666
Free PMC Article
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