Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Metab Syndr Relat Disord. 2006 Winter;4(4):315-27. doi: 10.1089/met.2006.4.315.

Glycemic control in the metabolic syndrome and implications in preventing cardiovascular disease.

Author information

  • Department of Medicine, University of Rochester School of Medicine, Rochester, New York.

Abstract

The metabolic syndrome represents a cluster of cardiovascular risk factors that occur together more commonly than expected from the prevalence of their individual rates. Insulin resistance is widely believed to be the common denominator causing, in susceptible individuals, the development of various cardiovascular risk factor components of the syndrome (e.g., hyperlipidemia, hypertension, and hyperglycemia). The major cause of this insulin resistance appears to be obesity, especially the accumulation of visceral fat. This obesity is due to the combination of excessive caloric intake and inadequate physical activity rather than alterations in energy utilization. In individuals whose beta cells cannot increase their insulin secretion adequately to compensate for insulin resistance, hyperglycemia occurs.

PMID:
18370749
[PubMed]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk