Send to:

Choose Destination
See comment in PubMed Commons below
Methods Mol Biol. 2008;415:365-77. doi: 10.1007/978-1-59745-570-1_21.

Reverse genetics analysis of antiparasitic responses in the malaria vector, Anopheles gambiae.

Author information

  • 1IBMC, Strasbourg, France.


Anopheles mosquitoes are the major vectors of human malaria parasites. Mosquito-parasite interactions are critical for disease transmission and therefore represent a potential target for malaria control strategies. Mosquitoes mount potent antiparasitic responses, and identification of mosquito factors that limit parasite development is one of the major objectives in the field. To address this question, we have developed a convenient reverse genetics approach by injection of double-stranded RNA (dsRNA) in adult mosquitoes, to evaluate the function of candidate genes in mosquito antiparasitic responses.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Write to the Help Desk