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Lab Chip. 2008 Apr;8(4):622-4. doi: 10.1039/b719029h. Epub 2008 Feb 18.

Shrinky-Dink microfluidics: 3D polystyrene chips.

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  • 1School of Engineering, University of California, Merced, USA.


We present a novel approach for the ultra-rapid direct patterning of complex three-dimensional, stacked polystyrene (PS) microfluidic chips. By leveraging the inherent shrinkage properties of biaxially pre-stressed thermoplastic sheets, microfluidic channels become thinner and deeper upon heating. Design conception to fully functional chips can thus be completed within minutes.

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