J Med Food. 2008 Mar;11(1):193-4.

Phytochemical investigation on leaf extract of Cordia salicifolia Cham.

Menghini L, Epifano F, Leporini L, Pagiotti R, Tirillini B.

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Dipartimento di Scienze del Farmaco, University G. D'Annunzio, Chieti Scalo, Italy. lmenghini@unich.it

Abstract

The dichloromethane extract of leaves of Cordia salicifolia Cham. (Family Boraginaceae) was fractionated by SiO(2) column chromatography and analyzed by gas chromatography, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectroscopy. The apolar extract is characterized by a very high content of (+)-spathulenol (0.53%). The major component of the extract exhibited a very weak activity as an inhibitor of growth of Helicobacter pylori in vitro (minimum inhibitory concentration = 200 microg/mL).

PMID:: 18361757; [PubMed - indexed for MEDLINE]

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