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1: Chem Biol. 2008 Mar;15(3):211-3.Click here to read Links

A forced march across an RNA folding landscape.

Silverman SK.

Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, IL 61801, USA.

In a recent issue of Science, Greenleaf et al. (2008) report single-molecule force measurements to explore the sequential folding landscape of an adenine riboswitch aptamer domain. This study provides an exceptionally quantitative view of how an RNA molecule folds.

PMID: 18355720 [PubMed - indexed for MEDLINE]