[Primary Gougerot-Sjogren's syndrome presenting as a cerebellar syndrome]

A Azeroual; A Benomar; H Harmouche; N Daoudi; E H Ait Benhaddou; M Yahyaoui; A Maaouni

doi:10.1016/S0035-3787(07)78411-4

[Primary Gougerot-Sjogren's syndrome presenting as a cerebellar syndrome]

Rev Neurol (Paris). 2007 Dec;163(12):1242-5. doi: 10.1016/S0035-3787(07)78411-4.

[Article in French]

Authors

A Azeroual¹, A Benomar, H Harmouche, N Daoudi, E H Ait Benhaddou, M Yahyaoui, A Maaouni

Affiliation

¹ Service de Neurologie B et de Neurogénétique, hôpital des spécialités de Rabat, Maroc; Service de Médecine Interne, Centre Hospitalier Ibn Sina, Rabat, Maroc.

PMID: 18355474
DOI: 10.1016/S0035-3787(07)78411-4

Abstract

Primary Sjogren's syndrome is an autoimmune exocrinopathy with various extraglandular complications. Central neurological manifestations were described in 20 percent of cases. Cerebellar syndrome is uncommon in Sjogren's syndrome, but can occur after diagnosis, or rarely as an inaugural sign of the disease. We report the case of a 54-year-old man who presented a cerebellar syndrome with xerostomy and xerophthalmos. The diagnosis of primary Sjorgren's syndrome was confirmed on the accessory salivary gland biopsy. The patient received oral and intravenous corticosteroid therapy associated with cyclophosphamide monthly. Outcome was good.

Publication types

Case Reports
English Abstract

MeSH terms

Adrenal Cortex Hormones / therapeutic use
Anti-Inflammatory Agents / therapeutic use
Biopsy
Cerebellar Diseases / diagnosis
Cerebellar Diseases / pathology*
Cyclophosphamide / therapeutic use
Humans
Immunoelectrophoresis
Immunoglobulin G / immunology
Immunosuppressive Agents / therapeutic use
L-Lactate Dehydrogenase / blood
Magnetic Resonance Imaging
Male
Middle Aged
Salivary Glands / pathology
Sjogren's Syndrome / diagnosis
Sjogren's Syndrome / pathology*

Substances

Adrenal Cortex Hormones
Anti-Inflammatory Agents
Immunoglobulin G
Immunosuppressive Agents
Cyclophosphamide
L-Lactate Dehydrogenase