Format

Send to:

Choose Destination
See comment in PubMed Commons below
Nat Rev Cancer. 2008 Apr;8(4):288-98. doi: 10.1038/nrc2349.

The distinctive biology of cancer in adolescents and young adults.

Author information

  • 1St Charles Medical Center, 2500 NE Neff Road, Bend, Oregon 97701, USA. ableyer@scmc.org

Abstract

One explanation for the relative lack of progress in treating cancer in adolescents and young adults is that the biology of malignant diseases in this age group is different than in younger and older persons, not only in the spectrum of cancers but also within individual cancer types and within the patient (host). Molecular, epidemiological and therapeutic outcome comparisons offer clues to this distinctiveness in most of the common cancers of adolescents and young adults. Translational and clinical research should not assume that the biology of cancers and patients is the same as in other age groups, and treatment strategies should be tailored to the differences.

PMID:
18354417
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk