J Peripher Nerv Syst. 2008 Mar;13(1):64-70. doi: 10.1111/j.1529-8027.2008.00159.x.

Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A.

Padua L, Shy ME, Aprile I, Cavallaro T, Pareyson D, Quattrone A, Rizzuto N, Vita G, Tonali P, Schenone A.

Source

Institute of Neurology, Università Cattolica del Sacro Cuore, Rome, Italy. lpadua@rm.unicatt.it

Abstract

Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.

PMID:: 18346232; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Grant Support

Publication Types

MeSH Terms

Grant Support

GUP02169/Telethon/Italy

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Charcot-Marie-Tooth Disease - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

Quality of life in patients with Charcot-Marie-Tooth disease. [Neurology. 2005]
Quality of life in patients with Charcot-Marie-Tooth disease.
Vinci P, Serrao M, Millul A, Deidda A, De Santis F, Capici S, Martini D, Pierelli F, Santilli V. Neurology. 2005 Sep 27; 65(6):922-4.
Variables influencing quality of life and disability in Charcot Marie Tooth (CMT) patients: Italian multicentre study. [Neurol Sci. 2006]
Variables influencing quality of life and disability in Charcot Marie Tooth (CMT) patients: Italian multicentre study.
Padua L, Aprile I, Cavallaro T, Commodari I, La Torre G, Pareyson D, Quattrone A, Rizzuto N, Vita G, Tonali P, et al. Neurol Sci. 2006 Dec; 27(6):417-23.
Relationship between clinical examination, quality of life, disability and depression in CMT patients: Italian multicenter study. [Neurol Sci. 2008]
Relationship between clinical examination, quality of life, disability and depression in CMT patients: Italian multicenter study.
Padua L, Aprile I, Cavallaro T, Commodari I, Pareyson D, Quattrone A, Rizzuto N, Vita G, Tonali P, Schenone A, et al. Neurol Sci. 2008 Jun; 29(3):157-62. Epub 2008 Jul 9.
Review Muscle biopsy abnormalities differ between Charcot-Marie-Tooth type 1 and 2: reflect different pathophysiology? [Exerc Sport Sci Rev. 2002]
Review Muscle biopsy abnormalities differ between Charcot-Marie-Tooth type 1 and 2: reflect different pathophysiology?
Borg K, Ericson-Gripenstedt U. Exerc Sport Sci Rev. 2002 Jan; 30(1):4-7.
Review [Charcot-Marie-Tooth disease: electromyography is still useful in diagnosis and classification]. [Rev Neurol (Paris). 1997]
Review [Charcot-Marie-Tooth disease: electromyography is still useful in diagnosis and classification].
Birouk N, Maisonobe T, Le Forestier N, Gouider R, Léger JM, Bouche P. Rev Neurol (Paris). 1997 Dec; 153(12):727-36.

See reviews... See all...

Cited by 2 PubMed Central articles

Review Quality of life in rare genetic conditions: a systematic review of the literature. [Am J Med Genet A. 2010]
Review Quality of life in rare genetic conditions: a systematic review of the literature.
Cohen JS, Biesecker BB. Am J Med Genet A. 2010 May; 152A(5):1136-56.
Fatigue, reduced sleep quality and restless legs syndrome in Charcot-Marie-Tooth disease: a web-based survey. [J Neurol. 2010]
Fatigue, reduced sleep quality and restless legs syndrome in Charcot-Marie-Tooth disease: a web-based survey.
Boentert M, Dziewas R, Heidbreder A, Happe S, Kleffner I, Evers S, Young P. J Neurol. 2010 Apr; 257(4):646-52. Epub 2009 Nov 24.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Correlation between clinical/neurophysiological findings and quality of life in ...
Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A.
J Peripher Nerv Syst. 2008 Mar ;13(1):64-70. doi: 10.1111/j.1529-8027.2008.00159.x.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: