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J Peripher Nerv Syst. 2008 Mar;13(1):64-70. doi: 10.1111/j.1529-8027.2008.00159.x.

Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A.

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  • 1Institute of Neurology, Università Cattolica del Sacro Cuore, Rome, Italy. lpadua@rm.unicatt.it

Abstract

Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.

PMID:
18346232
[PubMed - indexed for MEDLINE]
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