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    Laryngorhinootologie. 2008 Feb;87(2):112-7.

    [Uncommon case of paraganglioma syndrome in combination with malignant paraganglioma]

    [Article in German]

    Schmahl K, Atamna N, Schönijahn T, Lülsdorf P, Göller T, Jacob R.

    Abt. XIII, Pathologie, Bundeswehrzentralkrankenhaus Koblenz.

    BACKGROUND: Combination of paraganglioma syndrome and malignant paraganglioma is an uncommon disease worldwide. PATIENT: We report the case of a 69-year old man with a jugular-tympanal paraganglioma, who underwent surgery. Histopathological examination revealed a malignant paraganglioma. An other contralateral carotid-body and a tumor in the thyroid gland had been discovered during staging. The molecular results confirmed the existence of a paraganglioma syndrome. DISCUSSION: A malignant paraganglioma based on a hereditary paraganglioma syndrome is a rare described case in literature. On the background of the literature we discuss the pathology, pathogenesis, diagnostic and therapy of this disease.

    PMID: 18345539 [PubMed - indexed for MEDLINE]

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