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Internist (Berl). 2008 May;49(5):553-8. doi: 10.1007/s00108-008-2107-y.

[Hormone therapy with estrogens and gestagens in peri- and post-menopause].

[Article in German]

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  • 1Universitäts-Frauenklinik, Robert-Koch-Strasse 40, 37075, Göttingen, Deutschland.


Hormone therapy with estrogens (combined with progestin for women who have not been hysterectomized) is the most efficacious treatment for climacteric symptoms. A few years ago hormone therapy was considered to be an ideal prevention for cardio-vascular disease, osteoporosis, dementia and other diseases. Large prospective randomized trials have changed this paradigm. Hormone therapy should only be used with a clear indication (moderate to severe climacteric symptoms and - with limitations - prevention of osteoporosis). The lowest effective dose should be used for the shortest possible time.

[PubMed - indexed for MEDLINE]
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