Rev Med Interne. 2008 May;29(5):393-6. Epub 2007 Nov 20.

[Acitretin-induced pneumonia: an underestimated complication of treatment of psoriasis].

[Article in French]

Martzolff L, Huber M, Dukic R, Thannberger P, Kieffer C, Kieffer P.

Source

Service de médecine interne, centre hospitalier Saint-Morand, 68134 Altkirch cedex, France. lionel.martzolff@wanadoo.fr

Abstract

INTRODUCTION:

Retinoids are known to induce side effects which can be severe. Alveolar and interstitial pneumonia of uncertain pathogenesis can rarely occur when retinoid are used among patients with psoriasis.

EXEGESIS:

We report an observation of acute respiratory distress beginning 26 days after introduction of acitretin, a second-generation retinoid. Treatment withdrawal and corticotherapy allow a spectacular amelioration of respiratory conditions.

CONCLUSION:

Pneumonia induced by retinoid must be known as a side effect of treatment of psoriasis.

PMID:: 18339457; [PubMed - indexed for MEDLINE]

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