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    J Invest Dermatol. 2008 Apr;128(4):773-5.

    Vitamin D regulation of cathelicidin in the skin: toward a renaissance of vitamin D in dermatology?

    Segaert S.

    Department of Dermatology, University Hospital Leuven, Belgium. Siegfried.Segaert@med.kuleuven.be

    Comment on:

    1,25-Dihydroxyvitamin D(3), the active form of vitamin D, is a major regulator of the expression of the cationic antimicrobial peptide cathelicidin, not only in monocytes but also in epidermal keratinocytes. The involvement of cathelicidin in wound healing and skin diseases as diverse as psoriasis, rosacea, and atopic dermatitis may create new opportunities for the use of vitamin D in dermatology.

    PMID: 18337709 [PubMed - indexed for MEDLINE]

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    • Calcitriol (Rocaltrol®)

      Calcitriol is a form of vitamin D that is used to treat and prevent low levels of calcium in the blood of patients whose kidneys or parathyroid glands (glands in the neck that release natural substances to control the am...

    • Source: AHFS Consumer Medication Information

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