New steroidal derivatives synthesized using 3beta-...[Acta Pharm. 2008]

All Databases
PubMed
Nucleotide
Protein
Genome
Structure
OMIM
PMC
Journals
Books

Search for

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Acta Pharm. 2008 Mar 1;58(1):43-59. Links

New steroidal derivatives synthesized using 3beta-hydroxyandrosten-17-one as starting material.

Abd El-Latif NA, Abdulla MM, Amr AE.

Natural Compounds Department, National Research Center, Cairo Dokki, Egypt.

In this study, we synthesized some new substituted steroidal derivatives using 3beta-hydroxyandrosten-17-one (dehydroepiandrosterone) as starting material. The synthesized steroidal derivatives 1-11 were evaluated for their androgenic-anabolic activities compared to testosterone as positive control. Details of the synthesis, spectroscopic data and toxicity (LD50) of synthesized compounds are reported.

PMID: 18337207 [PubMed - as supplied by publisher]

Synthesis and antiandrogenic activity of some new 3-substituted androstano[17,16-c]-5'-aryl-pyrazoline and their derivatives. [Bioorg Med Chem. 2006]
Anticancer activities of some newly synthesized pyridine, pyrane, and pyrimidine derivatives. [Bioorg Med Chem. 2006]
Analytical strategies for the detection of non-labelled anabolic androgenic steroids in nutritional supplements. [Food Addit Contam. 2004]
Androsterone 3alpha-ether-3beta-substituted and androsterone 3beta-substituted derivatives as inhibitors of type 3 17beta-hydroxysteroid dehydrogenase: chemical synthesis and structure-activity relationship. [J Med Chem. 2005]
Steroidal derivatives. Part 1: some novel steroidal thiosemicarbazones. Their synthesis, anticancer and endocrinological activities. [Pharmazie. 1978]
» See all Related Articles...

Display Show

New steroidal derivatives synthesized using 3beta-hydroxyandrosten-17-one as starting material.

Related Articles