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1: Acta Pharm. 2008 Mar 1;58(1):43-59.Click here to read Links

New steroidal derivatives synthesized using 3beta-hydroxyandrosten-17-one as starting material.

Abd El-Latif NA, Abdulla MM, Amr AE.

Natural Compounds Department, National Research Center, Cairo Dokki, Egypt.

In this study, we synthesized some new substituted steroidal derivatives using 3beta-hydroxyandrosten-17-one (dehydroepiandrosterone) as starting material. The synthesized steroidal derivatives 1-11 were evaluated for their androgenic-anabolic activities compared to testosterone as positive control. Details of the synthesis, spectroscopic data and toxicity (LD50) of synthesized compounds are reported.

PMID: 18337207 [PubMed - as supplied by publisher]