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    Neurobiol Aging. 2009 Nov;30(11):1890-1. Epub 2008 Mar 11.

    No association of DAPK1 and ABCA2 SNPs on chromosome 9 with Alzheimer's disease.

    Minster RL, DeKosky ST, Kamboh MI.

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    Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA 15261, United States.

    Abstract

    Recently genetic variation in the DAPK1 and ABCA2 genes has been reported to be associated with late- and early-onset Alzheimer's disease (AD), respectively. We examined the most significant two single-nucleotide polymorphisms (SNPs) in DAPK1 in a large case-control cohort of late-onset subjects and matched controls and one of the most significant SNPs in ABCA2 in a small set of early-onset subjects as well. We did not detect associations with AD for any variation.

    PMID:
    18336955
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC2763561
    Free PMC Article

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