Acta Neurol Scand. 2008 Sep;118(3):198-202. Epub 2008 Mar 11.

Pallidal deep brain stimulation in the treatment of Meige syndrome.

Source

Department of Neurosurgery, University Hospital of Northern Sweden, Umeå, Sweden. patric.blomstedt@neuro.umu.se

Abstract

BACKGROUND:

Pallidal deep brain stimulation (DBS) of globus pallidus internus (Gpi) has emerged as an effective treatment for dystonia. The experience is however limited concerning focal dystonias and to date only a few cases of pallidal DBS in the treatment of Meige syndrome have been published.

METHODS/RESULTS:

We here present a patient with Meige syndrome in whom unilateral pallidal DBS failed to improve the axial symptoms, but bilateral stimulation resulted in a major improvement. The Burke-Fahn-Marsden score (BFM) improved by 71.5% and the patient's blepharospasm was abolished.

CONCLUSIONS:

The results suggest bilateral pallidal DBS may be an effective treatment for Meige syndrome.

PMID:: 18336624; [PubMed - indexed for MEDLINE]

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