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    Bioorg Med Chem Lett. 2008 Apr 1;18(7):2440-4. Epub 2008 Mar 5.

    Design, synthesis and antiproliferative properties of oligomers with chromophore units linked by amide backbones.

    Farrera-Sinfreu J, Aviñó A, Navarro I, Aymamí J, Beteta NG, Varón S, Pérez-Tomás R, Castillo-Avila W, Eritja R, Albericio F, Royo M.

    Source

    Combinatorial Chemistry Unit, Barcelona Scientific Park (PCB), Josep Samitier 1-5, E-08028 Barcelona, Spain.

    Abstract

    The preparation of oligomers made up of several chromophore units as compounds with potential fluorescent and antiproliferative properties is described. Specifically, chromophore units with protected-amino groups and one carboxylic group are described, together with methods to assemble these units using peptide chemistry. Some of these compounds have antiproliferative activity.

    PMID:
    18321705
    [PubMed - indexed for MEDLINE]

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