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    Ann Fr Anesth Reanim. 2008 Mar;27(3):261-4. Epub 2008 Mar 3.

    [Lactic acidosis associated with propofol during general anaesthesia for neurosurgery].

    [Article in French]

    Source

    Département d'anesthésie-réanimation, HIA Sainte-Anne, boulevard Sainte-Anne, 83800 Toulon, France. bordes.julien@neuf.fr

    Abstract

    Propofol infusion syndrome (PRIS) is a new clinical entity reported in critically ill patients. Lactic acidosis, cardiac failure and rhabdomyolysis are the features. Lactic acidosis related to short-term propofol administration has been described during general anaesthesia. Lactic acidosis could be an early marker of PRIS. We report here a case of very early lactic acidosis in a 66-year-old-man receiving propofol during a neurosurgery. The outcome was good after discontinuation of propofol.

    PMID:
    18313882
    [PubMed - indexed for MEDLINE]

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