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Cell Host Microbe. 2008 Feb 14;3(2):63-5. doi: 10.1016/j.chom.2008.01.004.

New pieces for the malaria liver stage puzzle: where will they fit?

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  • 1Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal.


Malaria starts with the infection of the liver by Plasmodium parasites. Although extensive analysis of Plasmodium has revealed the expression patterns of this parasite in every stage of its life cycle, the liver stage remained unexplored. Recently, Tarun et al. have published the first complete transcriptome and proteome analysis of this intriguing parasite stage, providing a list of potential candidate target genes for antimalarial vaccines and drugs.

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