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Philos Ethics Humanit Med. 2008 Feb 29;3:8.
Wolpert L.
Sadness and low levels of depression are adaptive since they lead the individual to try and make up a loss. By contrast, severe or clinical depression is not adaptive, but can be thought of as sadness having become malignant.
PMID: 18312654 [PubMed - indexed for MEDLINE]
PMCID: PMC2267800
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[Philos Trans R Soc Lond B Biol Sci. 2004]
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