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J Clin Microbiol. 2008 May;46(5):1818-23. doi: 10.1128/JCM.02255-07. Epub 2008 Feb 27.

Characterization of new staphylococcal cassette chromosome mec (SCCmec) and topoisomerase genes in fluoroquinolone- and methicillin-resistant Staphylococcus pseudintermedius.

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  • 1Institute of Veterinary Bacteriology, University of Bern, Länggass-Strasse 122, Postfach, CH-3001 Bern, Switzerland.

Abstract

Fluoroquinolone- and methicillin-resistant Staphylococcus pseudintermedius isolates harbor two new staphylococcal cassette chromosome mec (SCCmec) elements that belong to class A, allotype 3 (SCCmec II-III), and to the new allotype 5 (SCCmec VII). Analysis of the complete nucleotide sequences of the topoisomerase loci gyrB/gyrA and grlB/grlA revealed mutations involved in fluoroquinolone resistance.

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