African Americans have the greatest incidence of colorectal cancer than any other racial or ethnic group. This population's survival from colorectal cancer is lower than that in the White population. Increased incidence and mortality can be attributed to barriers such as lower screening rates, less use of diagnostic testing, decreased access to healthcare, cultural beliefs, and lack of education regarding healthcare practices and preventable disease. The first step in reducing morbidity and mortality is to educate healthcare providers concerning this population and their increased risk for colorectal cancer. Healthcare providers must promote screening, provide education, and incorporate simple screening tools into routine exams. Local health departments and community centers must reach out to the African American community and lend assistance with culturally appropriate education regarding this preventable cancer.