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World J Gastroenterol. 2008 Feb 28;14(8):1296-8.

A squamous metaplasia in a gastric ulcer scar of the antrum.

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  • 1Department of Internal Medicine Uijeongbu St. Mary's Hospital, 65-1 Geumo-dong, Uijeongbu 480-717, Korea.


An 81-year-old man presented with epigastric pain and weight loss for one month. He had a past history of pulmonary tuberculosis, 10 years ago. We performed a gastroscopy, which showed a linear depressed whitish gastric ulcer scar (0.8 cm in length) in the posterior wall of the prepyloric antrum. The result of biopsy was reported as squamous epithelium. Immunohistochemical staining using an antibody to high molecular weight cytokeratin (HMC) revealed positive staining in the squamous epithelium. Two years later, the lesion was followed up. The lesion remained at same site endoscopically, but no squamous epithelium could be seen microscopically.

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