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Dig Dis Sci. 2008 Aug;53(8):2251-7. doi: 10.1007/s10620-007-0121-x. Epub 2008 Feb 26.

Aspiration-sclerotherapy results in effective control of liver volume in patients with liver cysts.

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  • 1Department of Gastroenterology and Hepatology, University Medical Center St Radboud, Nijmegen, The Netherlands. L.vanKeimpema@MDL.umcn.nl

Abstract

PURPOSE:

To study the extent to which aspiration-sclerotherapy reduces liver volume and whether this therapy results in relief of symptoms.

RESULTS:

Four patients, group I, with isolated large liver cysts, and 11 patients, group II, with polycystic livers, underwent aspiration-sclerotherapy. Average volume of aspirated cyst fluid was 1,044 ml (range 225-2,000 ml) in group I and 1,326 ml (range 40-4,200 ml) in group II. Mean liver volume before the procedure was 2,157 ml (range 1,706-2,841 ml) in group I and 4,086 ml (range 1,553-7,085 ml) in group II. This decreased after the procedure to 1,757 ml (range 1,479-2,187 ml) in group I. In group II there was a statistically significant decrease to 3,347 ml (range 1,249-6,930 ml, P = 0.008). Volume reduction was 17.1% (range -34.7% to -4.1%) and 19.2% (range -53.9% to +2.4%) in groups I and II, respectively. Clinical severity of all symptoms decreased, except for involuntary weight loss and pain in group II.

CONCLUSION:

Aspiration-sclerotherapy is an effective means of achieving liver volume reduction and relief of symptoms.

PMID:
18299984
[PubMed - indexed for MEDLINE]
PMCID:
PMC2467533
Free PMC Article
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