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Universitätsklinik und Poliklinik für Kinder- und Jugendmedizin der Martin-Luther-Universität Halle-Wittenberg, Halle/Saale, Germany. michael.karremann@medizin.uni-halle.de
Both in Angelman-Syndrome and Graves' disease somatic and psychomotoric retardation, agitation and sleep disorder are major symptoms and signs. We report on the coincidence of both diseases in a 13 month old boy. Due to the overlapping pathology physicians should take special care on symptoms and signs of thyroid dysfunction in children with Angelman-Syndrome. In the case of coincidence a delayed diagnosis and treatment of hyperthyroidism could be avoided.
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