Center for Addiction Research, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA. ajbudney@uams.edu
The prevalence of marijuana abuse and dependence disorders has been increasing among adults and adolescents in the United States. This paper reviews the problems associated with marijuana use, including unique characteristics of marijuana dependence, and the results of laboratory research and treatment trials to date. It also discusses limitations of current knowledge and potential areas for advancing research and clinical intervention.