Bioinformatics. 2008 Apr 1;24(7):1026-8. Epub 2008 Feb 21.

GOTreePlus: an interactive gene ontology browser.

Source

Microsoft Research, One Microsoft Way, Redmond, WA 98052, USA.

Abstract

We developed an interactive gene ontology (GO) browser named GOTreePlus that superimposes annotation information over GO structures. It can facilitate the identification of important GO terms through interactive visualization of them in the GO structure. The interactive pie chart summarizing an annotation distribution for a selected GO term provides users with a succinct context-sensitive overview of their experimental results. We tested our GOTreePlus using a proteome profiling dataset obtained on differentiation of retinal pigment epithelial cells where 399 proteins were quantified. AVAILABILITY: http://bioinformatics.cnmcresearch.org/GOTreePlus/.

PMID:: 18292113; [PubMed - indexed for MEDLINE]

Free full text

Publication Types, MeSH Terms, Grant Support

Publication Types

Research Support, N.I.H., Extramural

MeSH Terms

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Medical

Genes and Gene Therapy - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

Ontology annotation treebrowser : an interactive tool where the complementarity of medical subject headings and gene ontology improves the interpretation of gene lists. [Appl Bioinformatics. 2006]
Ontology annotation treebrowser : an interactive tool where the complementarity of medical subject headings and gene ontology improves the interpretation of gene lists.
Bresell A, Servenius B, Persson B. Appl Bioinformatics. 2006; 5(4):225-36.
GOurmet: a tool for quantitative comparison and visualization of gene expression profiles based on gene ontology (GO) distributions. [BMC Bioinformatics. 2006]
GOurmet: a tool for quantitative comparison and visualization of gene expression profiles based on gene ontology (GO) distributions.
Doherty JM, Carmichael LK, Mills JC. BMC Bioinformatics. 2006 Mar 17; 7:151. Epub 2006 Mar 17.
NetAffx Gene Ontology Mining Tool: a visual approach for microarray data analysis. [Bioinformatics. 2004]
NetAffx Gene Ontology Mining Tool: a visual approach for microarray data analysis.
Cheng J, Sun S, Tracy A, Hubbell E, Morris J, Valmeekam V, Kimbrough A, Cline MS, Liu G, Shigeta R, et al. Bioinformatics. 2004 Jun 12; 20(9):1462-3. Epub 2004 Feb 12.
Review An overview of Spotfire for gene-expression studies. [Curr Protoc Bioinformatics. 2004]
Review An overview of Spotfire for gene-expression studies.
Kaushal D, Naeve CW. Curr Protoc Bioinformatics. 2004 Sep; Chapter 7:Unit 7.7.
Review The importance of biological databases in biological discovery. [Curr Protoc Bioinformatics. 2006]
Review The importance of biological databases in biological discovery.
Baxevanis AD. Curr Protoc Bioinformatics. 2006 Mar; Chapter 1:Unit 1.1.

See reviews... See all...

Cited by 1 PubMed Central article

SimCT: a generic tool to visualize ontology-based relationships for biological objects. [Bioinformatics. 2009]
SimCT: a generic tool to visualize ontology-based relationships for biological objects.
Herrmann C, Bérard S, Tichit L. Bioinformatics. 2009 Dec 1; 25(23):3197-8. Epub 2009 Sep 23.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

GOTreePlus: an interactive gene ontology browser.
GOTreePlus: an interactive gene ontology browser.
Bioinformatics. 2008 Apr 1 ;24(7):1026-8. Epub 2008 Feb 21 .

PubMed
G4-forming sequences in the non-transcribed DNA strand pose blocks to T7 RNA pol...
G4-forming sequences in the non-transcribed DNA strand pose blocks to T7 RNA polymerase and mammalian RNA polymerase II.
J Biol Chem. 2008 May 9 ;283(19):12756-62. Epub 2008 Feb 20 .

PubMed
Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory...
Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity.
Brain. 2008 Mar ;131(Pt 3):651-64.

PubMed
Clinical practice guidelines for the use of colony-stimulating factors in cancer...
Clinical practice guidelines for the use of colony-stimulating factors in cancer treatment: Implications for oncology nurses.
Eur J Oncol Nurs. 2008 Feb ;12(1):14-25.

PubMed
Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large...
Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study.
Osteoarthritis Cartilage. 2008 Sep ;16(9):1054-9. Epub 2008 Mar 4 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: