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1: J Am Acad Child Adolesc Psychiatry. 1991 May;30(3):471-8.Links
Comment in:
J Am Acad Child Adolesc Psychiatry. 1992 Mar;31(2):370-1.

Psychiatric disorders in the parents of autistic individuals.

Piven J, Chase GA, Landa R, Wzorek M, Gayle J, Cloud D, Folstein S.

Johns Hopkins University, School of Medicine, Department of Psychiatry, Baltimore, MD.

Eighty-one parents of 42 autistic probands and 34 parents of 18 Down syndrome probands were examined using a semistructured, investigator-based version of the Schedule for Affective Disorders and Schizophrenia Lifetime Version to estimate the lifetime risk of psychiatric disorder. The lifetime prevalence rate of anxiety disorder was significantly greater in parents of autistic probands than in parents of Down syndrome probands. The lifetime prevalence rate of major depressive disorder, while not significantly different in cases and controls, may be high in the parents of autistic probands (27%) in comparison with populations rates.

PMID: 1829081 [PubMed - indexed for MEDLINE]

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