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Nature. 2008 Feb 21;451(7181):949-52. doi: 10.1038/nature06802.

The search for new cardiovascular biomarkers.

Author information

  • 1Massachusetts General Hospital, Cardiology Division, 55 Fruit Street, Boston, Massachusetts 02114, USA. rgerszten@partners.org

Abstract

Despite considerable advances in the treatment of cardiovascular disease, it remains the leading cause of death in developed countries. Assessment of classic cardiovascular risk factors--including high blood pressure, diabetes and smoking--has a central role in disease prevention. However, many individuals with coronary heart disease (a narrowing of the blood vessels that supply the heart) have only one, or none, of the classic risk factors. Thus, new biomarkers are needed to augment the information obtained from traditional indicators and to illuminate disease mechanisms.

PMID:
18288185
[PubMed - indexed for MEDLINE]
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