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J Surg Oncol. 2008 Mar 15;97(4):298-313. doi: 10.1002/jso.20975.

Diagnosis and management of lipomatous tumors.

Author information

  • 1Department of Surgery, David Grant United States Air Force Medical Center, Travis Air Force Base, California 94535, USA. kimberlydalal@yahoo.com

Abstract

Lipomatous tumors range from benign lipomas to high-grade liposarcomas. Liposarcomas are classified into five histologic subtypes: well-differentiated, dedifferentiated, myxoid, round cell, and pleomorphic, which differ in outcomes and patterns of recurrence. Surgical resection is the mainstay of curative treatment; however, large, high grade liposarcomas may benefit from multimodality treatment with chemotherapy and radiation. A histologic-subtype specific nomogram provides accurate survival predictions. Prospective randomized clinical trials will continue to improve our care of patients with liposarcoma.

(c) 2008 Wiley-Liss, Inc.

PMID:
18286473
[PubMed - indexed for MEDLINE]
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