Your browser version may not work well with NCBI's Web applications. More information here...
1: J Am Acad Dermatol. 2008 Mar;58(3):505-7.Click here to read Links

Ichthyosis cribriformis: A new entity?

Larangeira de Almeida H Jr, Happle R, Blume-Peytavi U, de Castro LA.

Catholic and Federal University of Pelotas, Pelotas, Brazil. hiramalmeidajr@hotmail.com

A 22-year-old woman had an unusual congenital skin disorder in the form of ichthyosis characterized by innumerable keratotic plugs, resulting in a peculiar sievelike appearance. On histopathologic examination the epidermis showed a pronounced orthohyperkeratosis. The keratotic plugs seemed to emerge from the infundibular region of hair follicles. Immunohistochemical characterization revealed a normal keratin and filaggrin expression. Oral treatment with isotretinoin resulted in a reduction of the hyperkeratosis. Because we could not find any previously reported similar case, we propose the new name "ichthyosis cribriformis," which means "sievelike ichthyosis."

PMID: 18280353 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Isotretinoin (Accutane® , Amnesteem® , Claravis® , ...)

    Isotretinoin is used to treat severe recalcitrant nodular acne (a certain type of severe acne) that has not been helped by other treatments, such as antibiotics. Isotretinoin is in a class of medications called retinoids...

  • Source: AHFS Consumer Medication Information

Recent Activity