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Genome Biol. 2008;9(2):R34. doi: 10.1186/gb-2008-9-2-r34. Epub 2008 Feb 15.

Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes.

Author information

  • 1Computational Biology Unit, Bergen Center for Computational Science, University of Bergen, Thormøhlensgate, N-5008 Bergen, Norway. par.engstrom@bccs.uib.no

Abstract

Metazoan genomes contain arrays of highly conserved noncoding elements (HCNEs) that span developmental regulatory genes and define regulatory domains. We describe Ancora http://ancora.genereg.net, a web resource that provides data and tools for exploring genomic organization of HCNEs for multiple genomes. Ancora includes a genome browser that shows HCNE locations and features novel HCNE density plots as a powerful tool to discover developmental regulatory genes and distinguish their regulatory elements and domains.

PMID:
18279518
[PubMed - indexed for MEDLINE]
PMCID:
PMC2374709
Free PMC Article

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