J Affect Disord. 1991 Feb;21(2):141-7.

Treatment of seasonal affective disorder with high-intensity light. A phototherapy study with an Icelandic group of patients.

Source

Department of Psychiatry, National University Hospital, Reykjavik, Iceland.

Abstract

The standard phototherapy procedure for seasonal affective disorder (SAD) has been to expose patients to 2500 lux light intensity for 2 h. This study investigated whether high-intensity light treatment with a brief exposure time would relieve symptoms of SAD. Ten SAD patients were randomly assigned to 40-min exposure to 10,000 lux white light or to 400 lux red light which served as placebo. Each patient received treatment for 8 days, and after a wash-out period was crossed over to the other treatment condition. Depression was assessed by the 21-item HDRS and SIGH-SAD by a blind rater and the patients completed the BDI for self-assessment. Significantly greater improvement was found with 10,000 lux treatment than with the placebo (P = 0.011, P = 0.017 and P = 0.028 for SIGH-SAD, HDRS and BDI respectively). The 10,000 lux therapy improved the SIGH-SAD score by an average of 16.1 while the average improvement on placebo treatment was 5.0. The patients were rated again the following summer; most of them were the symptomless. Those patients who improved most on phototherapy also tended to improve most during the summer.

PMID:: 1827641; [PubMed - indexed for MEDLINE]

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