Drug Discov Today. 2008 Feb;13(3-4):118-23. Epub 2007 Nov 26.

Informatic innovations in glycobiology: relevance to drug discovery.

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Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji 611-0011, Japan. mami@kuicr.kyoto-u.ac.jp

Abstract

The recent development and applications of tree-based informatics on glycans have accelerated the biological analysis on glycans, particularly from structural viewpoints. We review three major aspects of recent informatics innovations on glycan structures: maturity of well-organized databases on glycan structures linking with other biological information, implementation of glycan structure matching algorithms and extensive development of methods for mining frequent patterns from glycan structures.

PMID:: 18275909; [PubMed - indexed for MEDLINE]

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