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Physiology (Bethesda). 2008 Feb;23:17-22. doi: 10.1152/physiol.00042.2007.

Beta-arrestins: multifunctional cellular mediators.

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  • 1Department of Biology, University of Haifa, Israel.


Initially thought to play a role only in G-protein-coupled receptor desensitization, beta-arrestins are ascribed with new roles such as scaffolding and signaling proteins by their own right. This review explores the many functions of beta-arrestins, with an emphasis on their recently identified role as regulators of receptor signaling.

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