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    Transplant Proc. 2008 Jan-Feb;40(1):302-4. doi: 10.1016/j.transproceed.2007.11.011.

    Successful therapy with rituximab of refractory acute humoral renal transplant rejection: a case report.

    Celik A, Saglam F, Cavdar C, Sifil A, Atila K, Sarioglu S, Bora S, Gulay H, Camsari T.

    Source

    Department of Nephrology, Dokuz Eylul University, School of Medicine, Balcova, Izmir, Turkey.

    Abstract

    Acute humoral rejection (AHR) is generally less responsive to conventional anti-rejection treatment with consequent allograft losses. Therapeutic options include antilymphocyte antibody (ATG), intravenous immunglobulin (IVIG), plasmapheresis, or immunoadsorption with protein A together with intensification of immunsuppression with a tacrolimus/mycophenolate mofetil combination. This report describes a transplant recipient who responded to rituximab therapy as treatment for steroid-, ATG-, IVIG-, and plasmapheresis-resistant AHR.

    PMID:
    18261611
    [PubMed - indexed for MEDLINE]

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