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Transplant Proc. 2008 Jan-Feb;40(1):77-80. doi: 10.1016/j.transproceed.2007.11.046.

Coronary artery calcifications in hemodialysis patients and their correlation with the prevalence of erectile dysfunction.

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  • 1Department of Urology, Hacettepe University, School of Medicine, Shihiye, Ankara, Turkey. kuinci@hacettepe.tr

Abstract

INTRODUCTION:

Our aim in this study was to investigate the prevalence and correlation with coronary artery calcium scores (CACS) and erectile dysfunction (ED) among hemodialysis patients.

PATIENTS AND METHODS:

Thirty-five male patients with chronic renal failure were selected to participate in this study. All patients underwent examinations for CACS using 16-channel multidetector computed tomography. The presence and severity of ED were determined by calculating the erectile function domain of the self-administered International Index of Erectile Function (IIEF).

RESULTS:

The patients' ages ranged from 22 to 78 with a mean of 51.6 years. The mean duration of hemodialysis was 75.7 months (range = 12 to 232). Twenty-six patients had a history of one or more systemic diseases. The prevalence of any level of ED was 82.9% for all hemodialysis patients, and severe ED, 40%. The CACS was significantly higher among patients with severe ED (P = .032). The IIEF-5 score was also shown to have a moderate negative correlation with the CACS (r = -.420, P = .012). Age, duration of hemodialysis, body mass index, diabetes mellitus, hypertension, coronary heart diseases, hyperlipidemia, thyroid disease, depression, tobacco consumption, and medication were not associated with the presence of ED (P > .05).

CONCLUSION:

ED is prevalent in hemodialysis patients. Although many possible factors contribute to ED, the severity of ED increases with greater CACS.

PMID:
18261550
[PubMed - indexed for MEDLINE]
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